MUSINGS PORTER 2020 Caption video

MUSINGS PORTER 2020 Caption video


I study proteins and proteins have been
thought to have one structure that has one function or fold I’m sending this
group of proteins called fold switching proteins so they can actually change
their structures and their functions in response to changes in the cell so you
can kind of imagine fold switching proteins are like a transformer where in
one case the protein is like a robot that does one thing and then in another
case in response to changes in our bodies it becomes a car and can do
something else and an advantage to this is it can
respond really quickly to changes in our bodies back in high school I did not
imagine myself being a scientist at all before going to college I did kind of
fall in love with math like when I took calculus I was like wow this is so cool
it was like the first time I realized that math could be useful for something
beyond balancing my checkbook at the end of my sophomore year of college my dad
was diagnosed with stage 4 lymphoma he went through multiple rounds of chemo
and it was just a really hard process just watching that happen and and like
thinking I wonder if there’s a better way some of the proteins that I’m
working on that actually do this phenomenon called fold switching are
actually associated with diseases so cancer Alzheimer’s autoimmune disease
bacterial and viral infections if by the end of my life even
one successful treatment was made based on this that would be amazing
NLM has a really strong track record in computation there are a lot of excellent
scientists here and so I thought it would be great to be able to work with
them. I’m also really grateful to have the freedom to pursue what I want
to do and I’m really happy to be here and be able to like take chances
that I probably couldn’t do in most other environments

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